(S,R,S)-AHPC-amido-C7-acid

(S,R,S)-AHPC-amido-C7-acid

• CAS Number: 2172819-76-8
• UNSPSC Description: (S,R,S)-AHPC-amido-C7-acid incorporates a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. (S,R,S)-AHPC-amido-C5-acid can be used to design PROTACs[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/s-r-s-ahpc-amido-c7-acid.html
• Solubility: DMSO : ≥ 100 mg/mL
• Smiles: OC(CCCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)=O)=O
• Molecular Weight: 600.77
• References & Citations: [1]Sun N, et al. Discovery of the First Lactate Dehydrogenase Proteolysis Targeting Chimera Degrader for the Treatment of Pancreatic Cancer. J Med Chem. 2023 Jan 12;66(1):596-610.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported