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Coronatine

CAT: 0804-HY-N11420-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N11420-01Size:1 mg
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Description
Coronatine is a plant growth regulator that mimicks the jasmonic acid-isoleucine conjugate (JA-Ile), targets the jasmonic acid receptor COI1, activates the jasmonic acid signaling pathway, thereby inhibiting salicylic acid (SA) -dependent defense responses. Coronatine antagonizes the stomatal closure, induces plant cell necrosis and chlorosis, interfers with plant hormone balance, thereby promoting pathogen infection[1][2][3][4].
CAS Number
62251-96-1
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; Phytohormone
Type
Natural Products
Related Pathways
Anti-infection; Others
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/coronatine.html
Purity
99.39
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C[C@H](CC)C[C@@]2([H])[C@]1([H])CCC2=O)N[C@]3(C[C@@H]3CC)C(O)=O
Molecular Formula
C18H25NO4
Molecular Weight
319.40
Precautions
H302, H315, H319, H335
References & Citations
[1] Geng X, et al. The phytotoxin coronatine is a multifunctional component of the virulence armament of Pseudomonas syringae. Planta. 2014 Dec;240 (6) :1149-65.|[2]Weiler EW, et al. The Pseudomonas phytotoxin coronatine mimics octadecanoid signalling molecules of higher plants. FEBS Lett. 1994 May 23;345 (1) :9-13. |[3] Zheng XY, et al. Coronatine promotes Pseudomonas syringae virulence in plants by activating a signaling cascade that inhibits salicylic acid accumulation. Cell Host Microbe. 2012 Jun 14;11 (6) :587-96. |[4]Li ZH, et al. Application of coronin as a novel cotton defoliator. State Intellectual Property Office of the People's Republic of China. CN102239876A.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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