Chenodeoxycholic acid 3-glucuronide

Chenodeoxycholic acid 3-glucuronide

• CAS Number: 58814-71-4
• UNSPSC Description: Chenodeoxycholic acid 3-glucuronide is a metabolite of Chenodeoxycholic acid that can activate the key nuclear receptor (FXR), with an EC50 of 8 μM, and in HEK293T cells, the EC50 for activating FXR is 11 μM[1].
• Target Antigen: FXR
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/chenodeoxycholic-acid-3-glucuronide.html
• Smiles: C[C@@]12[C@]3([H])[C@]([C@@H](C[C@]1([H])C[C@@H](CC2)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)C(O)=O)O)([H])[C@@]5([H])[C@](CC3)([C@@](CC5)([H])[C@H](C)CCC(O)=O)C
• Molecular Weight: 568.70
• References & Citations: [1]Serena Mostarda, et al. Synthesis, physicochemical properties, and biological activity of bile acids 3-glucuronides: Novel insights into bile acid signalling and detoxification. Eur J Med Chem. 2018 Jan 20:144:349-358.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported