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Rabbit anti Human LNX2

CAT: 0579-X2345PSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0579-X2345PSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interacts with the phosphotyrosine interaction domain of Numb. Lnx proteins may server as molecular scaffolds that localize unrelated, interacting proteins, such as Numb, to specific subcellular sites. Forms oligomers via their PDZ binding domains to PDZ-binding consensus motifs located in their C-termini or by homophilic oligomerization of their RING fingers.
CAS Number
9007-83-4
Synonyms
Numb-Binding Protein 2, PDZ Domain-containing RING finger Protein 1
UniProt
Q8N448
Host
Rabbit
Species Reactivity
Human
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Ammonium Sulfate Precipitation
Assay Principle
Antibody can be used for Western blotting (1-5 µg/mL). Optimal concentration should be evaluated by serial dilutions.
Stability
See expiration date on vial
Concentration
See vial for Concentration
Form
Provided as solution in phosphate buffered saline with 0,08% sodium azide
Precautions
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.
References & Citations
1. Rice, D.S., et al. 'The Lnx family proteins function as molecular scaffolds for Numb family proteins.' Mol Cell Neurosci. 2001 Nov;18(5):525-40. 2. Mirza, M., et al. 'The cell surface protein coxsackie- and adenovirus receptor (CAR) directly associates with the Ligand-of-Numb Protein-X2 (LNX2).' Exp Cell Res. 2005 Sep 10;309(1):110-20.
Shipping Conditions
Ambient Temperature, freeze upon arrival
Storage Conditions
Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles
Functional Analysis
WB

UniProtKB · Q8N448

Ligand of Numb protein X 2

LNX2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8N448
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LNX2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q5W0P0, Q6ZMH2, Q96SH4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

Metal-bindingZinc

Domain

RepeatZinc-finger

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