DBM-MMAF

DBM-MMAF

• CAS Number: 1810001-93-4
• UNSPSC Description: DBM-MMAF is a agent-linker conjugate composed of a potent antitubulin agent MMAF and a linker DBM to make antibody agent conjugate (ADC)[1].
• Target Antigen: Drug-Linker Conjugates for ADC
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/dbm-mmaf.html
• Smiles: C[C@@H](C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O)[C@H]([C@@](CCC2)([H])N2C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(CCCCCN(C3=O)C(C(Br)=C3Br)=O)=O)=O)=O)=O)OC
• Molecular Weight: 1082.95
• References & Citations: [1] Lee JW, et al. EphA2 targeted chemotherapy using an antibody drug conjugate in endometrial carcinoma. Clin Cancer Res. 2010 May 1;16(9):2562-70.
• Shipping Conditions: Room Temperature