Products for Research Use Only
RegisterLogin

R-75317

CAT: 0804-HY-119035Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-119035Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
R-75317 is a specific platelet-activating factor (PAF) antagonist. R-75317 can prevent the decline in creatinine clearance (Ccr) in a rat model of glomerulonephritis induced by the injection of antibodies extracted from rabbits against rat glomerular basement membrane (GBM) antigens, delay the onset of proteinuria, and improve glomerular hypertrophy, mesangial matrix proliferation, and interstitial fibrosis. R-75317 may be useful in the study of glomerulonephritis[1].
CAS Number
115406-25-2
UNSPSC
12352005
Target
Platelet-activating Factor Receptor (PAFR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/r-75317.html
Smiles
CCCCCCCCCCCCCCCCCNC(OC[C@@H](OC1=NOC=C1)COP(OCC[N+]2=CSC=C2)([O-])=O)=O
Molecular Formula
C29H50N3O8PS
Molecular Weight
631.76
References & Citations
[1]Miyamoto M, et al. The effects of R-75,317 on antiglomerular basement membrane glomerulonephritis in rats. Lipids. 1991 Dec;26 (12) :1316-9. doi: 10.1007/BF02536556.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-W998245(R, R, R) -AHPC (hydrochloride)
HY-W018061C-01(R, R) -Traxoprodil
HY-103451(R, R) -THC
HY-113834(R, R) -Ethambutol
HY-128888-01(R, R) -GSK321
HY-59125-01(R, R) - (+) -Hydrobenzoin
HY-100443B-01(R, R) -PX20606
HY-B0761(R, R) -Glycopyrrolate
HY-100741C-01(R, R) -S63845
HY-153321A-01(R, R) -Bexobrutideg

Alternative Products

CatalogName
T26022-01R 75317
TL505053Parpbp Mouse shRNA Plasmid (Locus ID 75317)
TL505053VParpbp Mouse shRNA Lentiviral Particle (Locus ID 75317)
SR417581Parpbp Mouse siRNA Oligo Duplex (Locus ID 75317)
TRC-O686450-50MG(R,R,R,R)-Orlistat
AR-P02420-01(R, R, R, R) -Benzylposaconazole
TRC-N387913-50MG(R,R,R,R)-Nebivolol
286046-01(R, R, R, R) -Orlistat
451679-01H-NBH (Mixture of Diastereomers) (R, S, R, R + R, R, R, R)
RM-S120712-01Saxagliptin (R, R, R, R) -Isomer

Popular Products