GAT2711

CAT: 0804-HY-161671-01Size: 5 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-161671-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

GAT2711 is a full agonist of α9 nAChR with an EC50 of 230 nM. GAT2711 shows 340-fold selective for α9 over α7 nAChRs. GAT2711 inhibits ATP-induced IL-1β release in THP-1 cells. GAT2711 retains full analgesic activity in α7 nAChR knockout mice[1].

UNSPSC

12352005

Target

NAChR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/gat2711.html

Purity

98.00

Solubility

DMSO : ≥ 100 mg/mL

Smiles

C[N+]1(CC)CCN(C2=CC=C(C=C2)NC(C3=NC(C)=CC=C3)=O)CC1.[I-]

Molecular Formula

C20H27IN4O

Molecular Weight

466.36

References & Citations

[1]Andleeb H, et al. Explorations of Agonist Selectivity for the α9* nAChR with Novel Substituted Carbamoyl/Amido/Heteroaryl Dialkylpiperazinium Salts and Their Therapeutic Implications in Pain and Inflammation. J Med Chem. 2024 Jun 13;67 (11) :8642-8666.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-113689-01	GAT211

Alternative Products

Catalog	Name
T209856-01	GAT2711

GAT2711

Related Products

Alternative Products

Popular Products