5-Methoxytryptamine (hydrochloride)

5-Methoxytryptamine (hydrochloride)

• CAS Number: 66-83-1
• UNSPSC Description: 5-Methoxytryptamine hydrochloride, a metabolite of Melatonin, is a nonselective 5-HT receptor agonist. 5-Methoxytryptamine hydrochloride has no affinity for the 5-HT3 receptor. 5-Methoxytryptamine hydrochloride is also a potent antioxidant and has radioprotective action[1][2][3].
• Target Antigen: 5-HT Receptor; Endogenous Metabolite
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling
• Field of Research: Cancer; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/5-methoxytryptamine-hydrochloride.html
• Purity: 98.0
• Solubility: 10 mM in DMSO
• Smiles: NCCC1=CNC2=C1C=C(OC)C=C2.[H]Cl
• Molecular Weight: 226.70
• References & Citations: [1]J Yamada, et al. Hyperglycemia induced by the 5-HT receptor agonist, 5-methoxytryptamine, in rats: involvement of the peripheral 5-HT2A receptor. Eur J Pharmacol. 1997 Apr 4;323(2-3):235-40. |[2]S Bayari, et al. Fourier transform infrared spectra and molecular structure of 5-methoxytryptamine, N-acetyl-5-methoxytryptamine and N-phenylsulfonamide-5-methoxytryptamine. Spectrochim Acta A Mol Biomol Spectrosc. 2003 Apr;59(6):1255-63.|[3]D A Craig, et al. 5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum. Naunyn Schmiedebergs Arch Pharmacol. 1990 Jul;342(1):9-16.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported