5-Methoxytryptamine

CAT: 0804-HY-W015169-01Size: 5 gDry Ice: NoHazardous: No
CAT#:0804-HY-W015169-01Size:5 g
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Description
5-Methoxytryptamine, a metabolite of Melatonin, is a nonselective 5-HT receptor agonist. 5-Methoxytryptamine has no affinity for the 5-HT3 receptor. 5-Methoxytryptamine is also a potent antioxidant and has radioprotective action[1][2][3].
CAS Number
[608-07-1]
Product Name Alternative
O-Methylserotonin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
5-HT Receptor; Drug Metabolite; Endogenous Metabolite
Type
Reference compound
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/2-5-methoxy-1h-indol-3-yl-ethanamine.html
Purity
99.91
Solubility
DMSO : 200 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic)
Smiles
COC1=CC2=C(NC=C2CCN)C=C1
Molecular Formula
C11H14N2O
Molecular Weight
190.25
Precautions
H302, H315, H319, H335
References & Citations
[1]J Yamada, et al. Hyperglycemia induced by the 5-HT receptor agonist, 5-methoxytryptamine, in rats: involvement of the peripheral 5-HT2A receptor. Eur J Pharmacol. 1997 Apr 4;323 (2-3) :235-40. |[2]S Bayari, et al. Fourier transform infrared spectra and molecular structure of 5-methoxytryptamine, N-acetyl-5-methoxytryptamine and N-phenylsulfonamide-5-methoxytryptamine. Spectrochim Acta A Mol Biomol Spectrosc. 2003 Apr;59 (6) :1255-63.|[3]D A Craig, et al. 5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum. Naunyn Schmiedebergs Arch Pharmacol. 1990 Jul;342 (1) :9-16.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Apolipoprotein D; Human Endogenous Metabolite; mLAG-3; MUC2; MUC3; Prostaglandin D Synthase; α-1 microglobulin

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