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Flumazenil

CAT: 0400-SIH-622-10MGSize: 10 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-622-10MGSize:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A benzodiazepine antagonist1, panspecific for 1,, or5-containing GABAA receptors2. Reduces withdrawal sequelae in benzodiazepine dependence3. Reverses the toxic effects, including coma and respiratory depression of zolpidem intoxication4 and gabapentin-induced coma5.
Description
Benzodiazepine antagonist
CAS Number
78755-81-4
Product Name Alternative
8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, ethyl ester; Ro 1722; Ro 15-1788
UNSPSC
41116105
Type
Antagonist
Source
Synthetic
Field of Research
Neuroscience | Neurotransmission | Neurotransmitter Receptors | GABA Receptors
Purity
>98% (HPLC) ; NMR (Conforms)
Weight
0.005
Format
White powder
Solubility
May be dissolved in DMSO (8 mg/ml)
Molecular Formula
C15H14FN3O3
Molecular Weight
303.3
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Möhler H., et al. (1981) J. Neurochem. 37:714. 2. Doble A., (1999) J. Psychopharmacol. 13(4 Suppl 1):S11. 3. Hood SD., et al. (2014) Br. J. Clin. Pharmacol. 77:285. 4. Lheureux P., et al.(1990) Hum. Exp. Toxicol. 9:105. 5. Masciullo M., et al. (2021) J. Med. Case Rep. 15:242.

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CatalogName
T1240-01Flumazenil

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