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Flumazenil

CAT: 0931-T1240-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T1240-01Size:1 mL - 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
78755-81-4
Target
GABA Receptor
Related Pathways
Neuroscience, Membrane transporter/Ion channel
Purity
>99.99%
Bioactivity
Flumazenil (Ro 15-1788) antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA) /benzodiazepine receptor complex in the central nervous system (CNS), thereby preventing the chloride channel opening events and inhibiting neuronal hyperpolarization. As a result, flumazenil reverses benzodiazepine-induced effects including sedation, psychomotor deficits, amnesia, and hypoventilation in a dose-dependent manner. Flumazenil is an imidazobenzodiazepine derivative, effective in reversing benzodiazepine-induced activities.
Smiles
CCOC(=O)c1ncn-2c1CN(C)C(=O)c1cc(F)ccc-21
Molecular Formula
C15H14FN3O3
Molecular Weight
303.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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