8-Br-NHD+

• Description:

  8-Br-NHD+ (Nicotinamide 8-Br-hypoxanthine dinucleotide) is a derivative of NAD+ (nicotinamide adenine dinucleotide) that acts as a potential substrate, competitive inhibitor or modulator of enzymes that interact with β-NAD+. 8-Br-NHD+ can be used to synthesize a cyclic ADP nucleotide (cADPR) analog[1].

• Product Name Alternative:

  Nicotinamide 8-Br-hypoxanthine dinucleotide

• UNSPSC:

  12352005

• Target:

  Drug Derivative

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/8-br-nhd.html

• Smiles:

  O[C@H]1[C@@H](O)[C@H](N2C(Br)=NC3=C2N=CNC3=O)O[C@@H]1COP(OP(OC[C@H]4O[C@@H]([N+]5=CC=CC(C(N)=O)=C5)[C@H](O)[C@@H]4O)([O-])=O)(O)=O

• Molecular Formula:

  C21H25BrN6O15P2

• Molecular Weight:

  743.31

• References & Citations:

  [1]Wagner G K, et al. Analogues of cyclic adenosine 5′-diphosphate ribose and adenophostin A, nucleotides in cellular signal transduction[C]//Nucleic acids symposium series. Oxford University Press, 2003, 3 (1) : 1-2.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [477782-33-5]