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Lasalocid (sodium)

CAT: 0804-HY-B1071A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1071A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lasalocid sodium (Lasalocid sodium-A) is an antibacterial and anticoccidial agent that can be used as feed additives. Lasalocid sodium exhibits antitumor activity. Lasalocid sodium is orally active[1][2][3].
CAS Number
25999-20-6
Product Name Alternative
Lasalocid-A (sodium) ; Ionophore X-537A (sodium) ; Antibiotic X-537A (sodium)
UNSPSC
12352005
Hazard Statement
H225, H302+H312+H332, H319
Target
Antibiotic; Apoptosis; Autophagy; Bacterial; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/Lasalocid-sodium.html
Concentration
10mM
Purity
99.03
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O[Na])C1=C(CC[C@@H](C)[C@H](O)[C@H](C)C([C@@H]([C@H]2O[C@@]([C@H]3CC[C@](O)(CC)[C@H](C)O3)(CC)C[C@@H]2C)CC)=O)C=CC(C)=C1O
Molecular Formula
C34H53NaO8
Molecular Weight
612.77
Precautions
H225, H302+H312+H332, H319
References & Citations
[1]Chen M, et al. Effect of monensin and lasalocid-sodium on the growth of methanogenic and rumen saccharolytic bacteria. Appl Environ Microbiol. 1979 Jul;38 (1) :72-7.|[2]Kim KY, et al., Lasalocid induces cytotoxic apoptosis and cytoprotective autophagy through reactive oxygen species in human prostate cancer PC-3 cells. Biomed Pharmacother. 2017 Apr;88:1016-1024.|[3]OZ HS, et al., Efficacy of lasalocid against murine Pneumocystis carinii pneumonitis. Antimicrob Agents Chemother. 1997 Jan;41 (1) :191-2.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Citation 01
Langmuir. 2020 Mar 31;36 (12) :3184-3192. |bioRxiv. 2023 Jun 25.|J Cancer. 2025 Jan 1;16 (3) :765-783.|Talanta. 2025 Apr 10:293:128128.

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