KRAS G12C inhibitor 14
CAT:
804-HY-125872-06
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
KRAS G12C inhibitor 14
- CAS Number: 2349393-95-7
- UNSPSC Description: KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 17, has an IC50 of 18 nM[1].
- Target Antigen: Ras
- Type: Reference compound
- Related Pathways: GPCR/G Protein;MAPK/ERK Pathway
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/kras-g12c-inhibitor-14.html
- Purity: 98.07
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: FC1=CC=CC(O)=[C@@]1[C@@]2=C(F)C(N=CC(N3C)=C4N5[C@H](CN(C(C=C)=O)CC5)C3=O)=C4C=C2Cl
- Molecular Weight: 484.88
- References & Citations: [1]Jason Grant Kettle, et al. Tetracyclic compounds as inhibitors of g12c mutant ras protein, for use as anti-cancer agents. WO2019110751A1.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: No Development Reported