KRAS G12C inhibitor 28
CAT:
804-HY-142460-01
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
KRAS G12C inhibitor 28
- CAS Number: 2649004-88-4
- UNSPSC Description: KRAS G12C inhibitor 28 is a KRAS G12C inhibitor with an IC50 of 57 nM. KRAS G12C inhibitor 28 has antitumor effects (WO2021113595A1; Example 1)[1].
- Target Antigen: Ras
- Type: Reference compound
- Related Pathways: GPCR/G Protein;MAPK/ERK Pathway
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/kras-g12c-inhibitor-28.html
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: O=C1N(C2=C(C(C)C)C=C(P(C)(C)=O)C=C2C)C3=NC(C4=C(O)C=CC=C4F)=C(F)C=C3C(N5[C@@H](C)CN(C(C=C)=O)CC5)=N1
- Molecular Weight: 635.64
- References & Citations: [1]Don Zhang, et al. Phosphorus derivatives as kras inhibitors. WO2021113595A1.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported