SJG-136 intermediate-2

• UNSPSC Description:

  SJG-136 intermediate-2 (compound 141) is an intermediate for synthesizing SJG-136. SJG-136 is a DNA cross-linking agent, with an XL50 of 45 nM for pBR322 DNA[1].

• Target Antigen:

  ADC Cytotoxin

• Type:

  Reference compound

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/sjg-136-intermediate-2.html

• Smiles:

  O=C(N1[C@@H](CC(C1)=C)CO[Si](C)(C)C(C)(C)C)C2=C(C=C(C(OC)=C2)O)NC(OCC=C)=O

• Molecular Weight:

  476.64

• References & Citations:

  [1]Haoying Song, et al. Pyrrolobenzodiazepine derivative and ligand-linker conjugate thereof. WO2021137646A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2246368-23-8