SJG-136 intermediate-2

SJG-136 intermediate-2

• CAS Number: 2246368-23-8
• UNSPSC Description: SJG-136 intermediate-2 (compound 141) is an intermediate for synthesizing SJG-136. SJG-136 is a DNA cross-linking agent, with an XL50 of 45 nM for pBR322 DNA[1].
• Target Antigen: ADC Cytotoxin
• Type: Reference compound
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/sjg-136-intermediate-2.html
• Smiles: O=C(N1[C@@H](CC(C1)=C)CO[Si](C)(C)C(C)(C)C)C2=C(C=C(C(OC)=C2)O)NC(OCC=C)=O
• Molecular Weight: 476.64
• References & Citations: [1]Haoying Song, et al. Pyrrolobenzodiazepine derivative and ligand-linker conjugate thereof. WO2021137646A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported