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SJG-136 intermediate-2

CAT: 0804-HY-402090Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-402090Size:1 Each
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Description
SJG-136 intermediate-2 (compound 141) is an intermediate for synthesizing SJG-136. SJG-136 is a DNA cross-linking agent, with an XL50 of 45 nM for pBR322 DNA[1].
CAS Number
2246368-23-8
UNSPSC
12352005
Target
ADC Payload
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sjg-136-intermediate-2.html
Smiles
O=C(N1[C@@H](CC(C1)=C)CO[Si](C)(C)C(C)(C)C)C2=C(C=C(C(OC)=C2)O)NC(OCC=C)=O
Molecular Formula
C24H36N2O6Si
Molecular Weight
476.64
References & Citations
[1]Haoying Song, et al. Pyrrolobenzodiazepine derivative and ligand-linker conjugate thereof. WO2021137646A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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