Procaterol (hydrochloride)

• UNSPSC Description:

  Procaterol hydrochloride is a selective intermediate-acting β2 adrenoreceptor agonist with an EC50 of 12.9 μM[1]. Procaterol hydrochloride can inhibit inflammation both in vivo and in vitro[2].

• Target Antigen:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/procaterol-hydrochloride.html

• Purity:

  99.0

• Solubility:

  DMSO : 30 mg/mL (ultrasonic;warming)

• Smiles:

  O=C1NC2=C(C([C@H](O)[C@H](NC(C)C)CC)=CC=C2O)C=C1.[H]Cl

• Molecular Weight:

  326.82

• References & Citations:

  [1]C Atgié, et al. Role of beta1- and beta3-adrenoceptors in the regulation of lipolysis and thermogenesis in rat brown adipocytes. Am J Physiol. 1997 Oct;273(4):C1136-42.|[2]Zheng Deng, et al. Procaterol but not dexamethasone protects 16HBE cells from H₂O₂-induced oxidative stress. J Pharmacol Sci. 2014;125(1):39-50.|[3]Yiran Gu, et al. A brainstem-central amygdala circuit underlies defensive responses to learned threats. Mol Psychiatry. 2020 Mar;25(3):640-654.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  Launched

• CAS Number:

  62929-91-3