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Methyl tanshinonate

CAT: 0804-HY-126416-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-126416-01Size:1 mg
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Description
Methyl tanshinonate is a tanshinone, that can be isolated from Salvia miltiorrhiza (S. miltiorrhiza) Bunge (Lamiaceae) . Methyl tanshinonate is a potent inhibitor of Mpro enzyme in SARS-CoV (IC50 = 21.1 µM) . Methyl tanshinonate can be used for diabetes and SARS-CoV research[1][2][3].
CAS Number
18887-19-9
UNSPSC
12352005
Target
SARS-CoV
Type
Natural Products
Related Pathways
Anti-infection
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/methyl-tanshinonate.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(CCC[C@]3(C)C(OC)=O)C3=CC=C2C4=C(C(C)=CO4)C1=O
Molecular Formula
C20H18O5
Molecular Weight
338.35
References & Citations
[1]Kim DH, et al. Characterization of the inhibitory activity of natural tanshinones from Salvia miltiorrhiza roots on protein tyrosine phosphatase 1B. Chem Biol Interact. 2017 Dec 25;278:65-73.|[2]Ni L, et al. Qualitative analysis of the roots of Salvia miltiorrhiza and Salvia yunnanensis based on NIR, UHPLC and LC-MS-MS. J Pharm Biomed Anal. 2019 Jun 5;170:295-304.|[3]Diniz LRL, et al. Bioactive Terpenes and Their Derivatives as Potential SARS-CoV-2 Proteases Inhibitors from Molecular Modeling Studies. Biomolecules. 2021 Jan 7;11 (1) :74.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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