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NSD3 rabbit pAb

CAT: 0855-ES14448-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES14448-01Size:50 µL
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Background
This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described. [provided by RefSeq, May 2015]
Description
This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described. [provided by RefSeq, May 2015],
UniProt
Q9BZ95
Swiss Prot
Q9BZ95
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human NSD3 AA range: 1373-1423
Target
NSD3
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleus . Chromosome .
Gene ID (Human)
54904

UniProtKB · Q9BZ95

Histone-lysine N-methyltransferase NSD3

NSD3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9BZ95
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NSD3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.1.1.370, 2.1.1.371
Processing
—
Secondary accessions
B7ZL11, D3DSX1, Q1RMD3, Q3B796, Q6ZSA5, Q9BYU8, Q9BYU9, Q9H2M8, Q9H9W9, Q9NXA6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Molecular function

Chromatin regulatorMethyltransferaseTransferase

Cellular component

ChromosomeNucleus

Domain

Coiled coilRepeatZinc-finger

Ligand

Metal-bindingS-adenosyl-L-methionineZinc

Disease

Proto-oncogene

Biological process

TranscriptionTranscription regulation