Lenalidomide-C6-Br

• Description:

  Lenalidomide-C6-Br is a conjugate of E3 ligase ligand and linker. Lenalidomide-C6-Br can be utilized for synthesis of PROTAC EGFR degrader 9 (HY-161536) [1].

• UNSPSC:

  12352005

• Target:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/lenalidomide-c6-br.html

• Smiles:

  O=C(CCCCCCBr)NC1=CC=CC2=C1CN(C2=O)C3C(NC(CC3)=O)=O

• Molecular Formula:

  C20H24BrN3O4

• Molecular Weight:

  450.33

• References & Citations:

  [1]Yasheng Zhu, et al. Design, Synthesis, and Biological Evaluation of Novel EGFR PROTACs Targeting C797S Mutation. J Med Chem. 2024 May 9;67 (9) :7283-7300.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2580970-60-9