Tubulin polymerization-IN-63

• UNSPSC Description:

  Tubulin polymerization-IN-63 (compound 6) is a tubulin polymerization inhibitor. The IC50 value of Tubulin polymerization-IN-63 for MES-SA cells is 0.29 μM. Tubulin polymerization-IN-63 can be used in cancer research[1].

• Target Antigen:

  Microtubule/Tubulin

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Cytoskeleton

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/tubulin-polymerization-in-63.html

• Smiles:

  Cl[Cu]12([N]3(C4)CCOCC3)[N](N=C(NC5=CC(C)=C(O)C(C)=C5)S2)=CC6=CC=CC4=[N]61

• Molecular Weight:

  497.50

• References & Citations:

  [1]Milunovic MNM, et al. Copper(II) Complexes with Isomeric Morpholine-Substituted 2-Formylpyridine Thiosemicarbazone Hybrids as Potential Anticancer Drugs Inhibiting Both Ribonucleotide Reductase and Tubulin Polymerization: The Morpholine Position Matters. J Med Chem. 2024 Jun 13;67(11):9069-9090.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3040385-73-4