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Cytogenin

CAT: 0804-HY-19606Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19606Size:1 Each
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Description
Cytogenin (Antibiotic MI 43-37F11) is an orally active antineoplastic antibiotic. Cytogenin regulates the inflammatory cytokine, reduces the levels of iNOS, NO and IL-6 in mouse macrophages, and exhibits antidiabetic efficacy in mice. Cytogenin inhibits growth of Ehrlich ascites tumor in mouse model[1][2][3].
CAS Number
132971-59-6
Product Name Alternative
Antibiotic MI 43-37F11
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Interleukin Related; NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cytogenin.html
Smiles
O=C1OC(CO)=CC2=C1C(O)=CC(OC)=C2
Molecular Formula
C11H10O5
Molecular Weight
222.19
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Kumagai H, et al., Biosynthesis of antitumor antibiotic, cytogenin. J Antibiot (Tokyo) . 1994 Apr;47 (4) :440-6. |[2]Kumagai H, et al., Cytogenin, a novel antitumor substance. J Antibiot (Tokyo) . 1990 Nov;43 (11) :1505-7. |[3]Kumagai H, et al., Effect of cytogenin, a novel immunomodulator, on streptozotocin-induced diabetes in mice. J Antibiot (Tokyo) . 2005 Mar;58 (3) :202-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19229874-01Cytogenin

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