Human Asialoglycoprotein Receptor 1 Extracellular Domain (recombinant)

• Description:

  Human Asialoglycoprotein Receptor 1 Extracellular Domain (recombinant)_x000D_ Catalog number: B2016799_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 50 µg_x000D_ Molecular Weight or Concentration: 28.8 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: ASGPR1, ASGR1, C-type Lectin Domain Family 4 Member H1, CLEC4H1, Hepatic Lectin H1_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Wymann S, Mischnik M, Leong D, Ghosh S, Tan X, Cao H, Kuehnemuth B, Powers GA, Halder P, de Souza MJ, James HS, Tomasetig V, Lind H, Rossato P, Owczarek CM, Ow SY, Dower SK, Baz Morelli A, Rowe T, Hardy MP. Sialylation-dependent pharmacokinetics and differential complement pathway inhibition are hallmarks of CR1 activity in vivo Biochem J. 2022 May 13;479(9):1007-1030._x000D_ 2: Aldworth H, Hooper NM. Post-translational regulation of the low-density lipoprotein receptor provides new targets for cholesterol regulation Biochem Soc Trans. 2024 Feb 28;52(1):431-440._x000D_ 3: Coombs PJ, Graham SA, Drickamer K, Taylor ME. Selective binding of the scavenger receptor C-type lectin to Lewisx trisaccharide and related glycan ligands J Biol Chem. 2005 Jun 17;280(24):22993-9._x000D_ 4: Liao KW, Chou WC, Lo YC, Roffler SR. Design of transgenes for efficient expression of active chimeric proteins on mammalian cells Biotechnol Bioeng. 2001 May 20;73(4):313-23._x000D_ 5: Wragg S, Drickamer K. Identification of amino acid residues that determine pH dependence of ligand binding to the asialoglycoprotein receptor during endocytosis J Biol Chem. 1999 Dec 10;274(50):35400-6._x000D_ 6: Weitzhandler M, Streeter HB, Henzel WJ, Bernfield M. The cell surface proteoglycan of mouse mammary epithelial cells. The extracellular domain contains N terminus and a peptide sequence present in a conditioned medium proteoglycan J Biol Chem. 1988 May 25;263(15):6949-52._x000D_ 7: Xu YF, Meyer AN, Webster MK, Lee BA, Donoghue DJ. The v-sis protein retains biological activity as a type II membrane protein when anchored by various signal-anchor domains, including the hydrophobic domain of the bovine papilloma virus E5 oncoprotein J Cell Biol. 1993 Nov;123(3):549-60._x000D_ 8: Atoda H, Hyuga M, Morita T. The primary structure of coagulation factor IX/factor X-binding protein isolated from the venom of Trimeresurus flavoviridis. Homology with asialoglycoprotein_receptors, proteoglycan core protein, tetranectin, and lymphocyte Fc epsilon receptor for immunoglobulin E J Biol Chem. 1991 Aug 15;266(23):14903-11._x000D_ 9: López-Cabrera M, Santis AG, Fernández-Ruiz E, Blacher R, Esch F, Sánchez-Mateos P, Sánchez-Madrid F. Molecular cloning, expression, and chromosomal localization of the human earliest lymphocyte activation antigen AIM/CD69, a new member of the C-type animal lectin superfamily of signal-transmitting receptors J Exp Med. 1993 Aug 1;178(2):537-47._x000D_ 10: Zeng FY, Oka JA, Weigel PH. The human asialoglycoprotein receptor is palmitoylated and fatty deacylation causes inactivation of state 2 receptors Biochem Biophys Res Commun. 1996 Jan 5;218(1):325-30. _x000D_ _x000D_ Products Related to Human Asialoglycoprotein Receptor 1 Extracellular Domain (recombinant) can be found at Proteins

• Short Description:

  Catalog Number: B2016799 (50 µg)_x000D_ Human Asialoglycoprotein Receptor 1 Extracellular Domain (recombinant) is a high quality protein that is produced using genetic engineering techniques. This protein is a part of the human asialoglycoprotein receptor 1, which is a cell surface receptor involved in the recognition and clearance of glycoproteins from the bloodstream. The extracellular domain of this receptor is the part of the protein that is located outside of the cell and is responsible for binding to specific ligands. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3