Human GABA Beta3 Receptor

• Description:

  Human GABA Beta3 Receptor_x000D_ Catalog number: B2016543_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 25 µg_x000D_ Molecular Weight or Concentration: N/A_x000D_ Supplied as: N/A_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: N/A_x000D_ Keywords: Gamma-Aminobuytric Acid Type A Receptor Beta 3 Subunit, GABA(A)Receptor, Beta 3_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR. Differential assembly diversifies GABA(A) receptor structures and signalling Nature. 2022 Apr;604(7904):190-194._x000D_ 2: Nakane T, Kotecha A, Sente A, McMullan G, Masiulis S, Brown PMGE, Grigoras IT, Malinauskaite L, Malinauskas T, Miehling J, Uchański T, Yu L, Karia D, Pechnikova EV, de Jong E, Keizer J, Bischoff M, McCormack J, Tiemeijer P, Hardwick SW, Chirgadze DY, Murshudov G, Aricescu AR, Scheres SHW. Single-particle cryo-EM at atomic resolution Nature. 2020 Nov;587(7832):152-156._x000D_ 3: Ratra GS, Kamita SG, Casida JE. Role of human GABA(A) receptor beta3 subunit in insecticide toxicity Toxicol Appl Pharmacol. 2001 May 1;172(3):233-40._x000D_ 4: Amrutkar RD, Ranawat MS. Microwave Assisted Synthesis and Molecular Docking Studies of Some 4- (3H)-quinazolinone Derivatives as Inhibitors of Human Gamma- Aminobutyric Acid Receptor, the GABA (A)R-BETA3 Homopentamer Med Chem. 2021;17(5):453-461._x000D_ 5: Laverty D, Desai R, Uchański T, Masiulis S, Stec WJ, Malinauskas T, Zivanov J, Pardon E, Steyaert J, Miller KW, Aricescu AR. Cryo-EM structure of the human α1β3γ2 GABA(A) receptor in a lipid bilayer Nature. 2019 Jan;565(7740):516-520._x000D_ 6: Qu S, Jackson LG, Zhou C, Shen D, Shen W, Nwosu G, Howe R, Catron MA, Flamm C, Biven M, Kang JQ, Macdonald RL. Heterozygous GABA(A) receptor β3 subunit N110D knock-in mice have epileptic spasms Epilepsia. 2023 Apr;64(4):1061-1073._x000D_ 7: Cao T, Chen H, Huang W, Xu S, Liu P, Zou W, Pang M, Xu Y, Bai X, Liu B, Rong L, Cui ZK, Li M. hUC-MSC-mediated recovery of subacute spinal cord injury through enhancing the pivotal subunits β3 and γ2 of the GABA(A) receptor Theranostics. 2022 Mar 28;12(7):3057-3078._x000D_ 8: Menzikov SA, Zaichenko DM, Moskovtsev AA, Morozov SG, Kubatiev AA. Ectopic GABA(A) receptor β3 subunit determines Cl(-) / HCO3- -ATPase and chloride transport in HEK 293FT cells FEBS J. 2021 Jan;288(2):699-712._x000D_ 9: Söderhielm PC, Klein AB, Bomholtz SH, Jensen AA. Profiling of GABA(A) and GABA(B) receptor expression in the myometrium of the human uterus Life Sci. 2018 Dec 1;214:145-152._x000D_ 10: Chopra A. Ethyl 8-fluoro-5-[(11)C]methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 2008 Apr 28 [updated 2008 Jun 10]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013._x000D_ _x000D_ Products Related to Human GABA Beta3 Receptor can be found at Proteins

• Short Description:

  Catalog Number: B2016543 (25 µg)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5