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Recombinant Human RPE65

CAT: 0710-P8510-01Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0710-P8510-01Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
All-trans-retinyl-palmitate hydrolase, LCA 2, LCA2, Leber congenital amaurosis, mRPE 65, mRPE65, p63, rd 12, rd12, Retinal pigment epithelium specific 61 kDa protein, Retinol isomerase, RP 20, RP20, RPE 65, RPE65, RPE65_HUMAN, sRPE 65, sRPE65
UniProt
Q16518
Expression Region
301-533
Host
E.Coli
Tag
N-terminal His-IF2DI Tag
Applications
Western Blot, ELISA
Field of Research
Neuroscience, Metabolism
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Lyophilized powder
Reconstitution
Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/ml by gently pipetting 2-3 times, don't vortex.
Molecular Weight
47.4 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
The lyophilized protein is stable at -20 °C for up to 1 year. For extended storage, it is recommended to further dilute in working aliquots after reconstitution. The protein solution is stable at ≤ -20 °C for 3 months, or 2-7 days at 2-8 °C under sterile conditions.Avoid repeated freeze/thaw cycle.
Formulation
Lyophilized from a 0.2 μm filtered solution of 10 mM Hepes, 150 mM NaCl with 5% trehalose, pH 7.4.
Organism Species
Human

UniProtKB · Q16518

Retinoid isomerohydrolase

RPE65_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q16518
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RPE65
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.1.1.64
Processing
—
Secondary accessions
A8K1L0, Q5T9U3
Protein keywords

PTM

AcetylationLipoproteinPalmitatePhosphoprotein

Cellular component

Cell membraneCytoplasmEndoplasmic reticulumMembraneMicrosome

Technical term

Direct protein sequencingProteomics identificationReference proteome

Disease

Disease variantLeber congenital amaurosisRetinitis pigmentosa

Molecular function

HydrolaseIsomerase

Ligand

IronMetal-binding

Biological process

Lipid metabolismSensory transductionVision

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