GSK3-IN-1

• UNSPSC Description:

  GSK3-IN-1 (compound 11) is a GSK-3 inhibitor with an IC50 value of 12 μM. GSK3-IN-1 can be used in the research of diabetes[1].

• Target Antigen:

  GSK-3

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR;Stem Cell/Wnt

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/gsk3-in-1.html

• Purity:

  99.86

• Solubility:

  DMSO : 100 mg/mL (ultrasonic;warming;heat to 52°C)

• Smiles:

  ClC1=C(CSC2=NN=C(C3=CC=NC=C3)O2)C=CC=C1

• Molecular Weight:

  303.774

• References & Citations:

  [1]Lars Naerum, et al. Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1525-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  478482-74-5