NLRP3-IN-2 (Standard)

NLRP3-IN-2 (Standard)

• CAS Number: 16673-34-0
• UNSPSC Description: NLRP3-IN-2 (Standard) is the analytical standard of NLRP3-IN-2. This product is intended for research and analytical applications. NLRP3-IN-2, an intermediate substrate in the synthesis of glyburide, inhibits the formation of the NLRP3 inflammasome in cardiomyocytes and limits the infarct size following myocardial ischemia/reperfusion in the mouse, without affecting glucose metabolism[1].
• Target Antigen: NOD-like Receptor (NLR)
• Type: Reference Standards
• Related Pathways: Immunology/Inflammation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/nlrp3-in-2-standard.html
• Smiles: O=C(NCCC1=CC=C(S(=O)(N)=O)C=C1)C2=CC(Cl)=CC=C2OC
• Molecular Weight: 368.84
• References & Citations: [1]Carlo Marchetti, et al. A novel pharmacologic inhibitor of the NLRP3 inflammasome limits myocardial injury after ischemia-reperfusion in the mouse. J Cardiovasc Pharmacol. 2014 Apr;63(4):316-322.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported