NPC 17731

CAT: 0804-HY-P1721Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P1721Size:1 Each
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Description
NPC 17731 is a new bradykinin (BK) receptor antagonist. NPC 17731 antagonized both the contractile and relaxant responses caused by BK in longitudinal smooth muscle with IC50 of 23 and 29 nM, respectively[1].
CAS Number
[147267-10-5]
UNSPSC
12352209
Target
Bradykinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/npc-17731.html
Smiles
O=C([C@@H]1N(C[C@H](C1)OCCC)C([C@H](CO)NC([C@@H](NC(CNC([C@H]2N(C[C@@H](C2)O)C([C@H]3N(CCC3)C([C@H](CCCNC(N)=N)NC([C@H](N)CCCNC(N)=N)=O)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)N5[C@]6([H])[C@](CCCC6)([H])C[C@H]5C(N[C@H](C(O)=O)CCCNC(N)=N)=O
Molecular Formula
C59H95N19O14
Molecular Weight
1294.50
References & Citations
[1]Y S Medeiros, et al. Competitive and selective antagonistic action of NPC 17731 on bradykinin-induced relaxant and contractile responses of the guinea pig isolated ileum. Gen Pharmacol. 1995 Nov;26 (7) :1507-11.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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