NPC 200

• Description:

  NPC 200 is a potent and selective antagonist of Adenosine A1 Receptor. NPC 200 reverses NECA-induced left and right atrial depression with EC50s of 1.08 and 2.03 μM[1].

• Product Name Alternative:

  1,3-Dipropyl-8-phenylxanthine

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Adenosine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/npc-200.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1CCC)N(CCC)C2=C(N=C(C3=CC=CC=C3)N2)C1=O

• Molecular Formula:

  C17H20N4O2

• Molecular Weight:

  312.37

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]P. V. Kaplita, et al. NPC 205 is a potent and selective adenosine A1, receptor antagonist: Correlation among receptor binding, biochemical, and physiological assays. , 20 (4), 429–443.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [85872-53-3]