NPC 200

• Description :

  NPC 200 is a potent and selective antagonist of Adenosine A1 Receptor. NPC 200 reverses NECA-induced left and right atrial depression with EC50s of 1.08 and 2.03 μM[1].

• Product Name Alternative :

  1,3-Dipropyl-8-phenylxanthine

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Adenosine Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/npc-200.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N1CCC)N(CCC)C2=C(N=C(C3=CC=CC=C3)N2)C1=O

• Molecular Formula :

  C17H20N4O2

• Molecular Weight :

  312.37

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]P. V. Kaplita, et al. NPC 205 is a potent and selective adenosine A1, receptor antagonist: Correlation among receptor binding, biochemical, and physiological assays. , 20 (4), 429–443.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature 3 years

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [85872-53-3]