Products for Research Use Only
RegisterLogin

Neostigmine (Bromide)

CAT: 0804-HY-B0423-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0423-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Neostigmine (Eustigmin) Bromide is an orally active and reversible cholinesterase inhibitor that acts on myasthenia gravis to prolong and intensify the muscarinic and nicotinic effects of acetylcholine. Neostigmine Bromide can be used in anesthesia to reverse the neuromuscular blockade produced by competitive neuromuscular blockers[1][2][3][4].
CAS Number
114-80-7
Product Name Alternative
Eustigmin bromide; Neoserine bromide
UNSPSC
12352005
Hazard Statement
H300+H310+H330, H315, H317, H319, H334, H335
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/neostigmine-bromide.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
C[N+](C)(C)C1=CC=CC(OC(N(C)C)=O)=C1.[Br-]
Molecular Formula
C12H19BrN2O2
Molecular Weight
303.20
Precautions
H300+H310+H330, H315, H317, H319, H334, H335
References & Citations
[1]Nanjwade B K, et al. Development and evaluation of intranasal mucoadhesive microspheres of neostigmine bromide[J]. Pharm Anal Acta, 2011, 2 (2) : 1-6.|[2]Khorshid AF, et al. Modified carbon paste sensor for the potentiometric determination of neostigmine bromide in pharmaceutical formulations, human plasma and urine. Biosens Bioelectron. 2014 Jan 15;51:143-9. |[3]SCHWAB RS, et al. Treatment of myasthenia gravis; prolonged action with multiple-dose tablets of neostigmine bromide and mestinon bromide. J Am Med Assoc. 1957 Oct 12;165 (6) :671-4.|[4]Makkar R, et al. Development and validation of a stability-indicating method for neostigmine bromide: separation, identification and characterization of degradation product using LC-MS and ESI-Q-TOF-MS/MS[J]. Indian Journal of Pharmaceutical Sciences, 2022, 56: 1-13.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Launched

Related Products

CatalogName
HY-126175Neostigmine (iodide)
HY-119792ANeostigmine (hydroxide)
HY-B1206-01Neostigmine (methyl sulfate)
HY-143542S-01Nor neostigmine-d6
HY-B1206R-01Neostigmine (methyl sulfate) (Standard)
HY-106024AAlagebrium (bromide)
HY-Y1100-01Cyclopropylmethyl bromide
HY-17632-01Tarloxotinib (bromide)
HY-D0172-01Tetrabutylammonium (bromide)
HY-B0547A-01Homatropine (Bromide)

Alternative Products

CatalogName
B1594-500Neostigmine Bromide
MBS385998-01Neostigmine bromide (Prostigmin)
RM-N051506-01Neostigmine Bromide Impurity 6
RM-N051516-01Neostigmine Bromide Impurity 16
RM-N051511-01Neostigmine Bromide Impurity 11
A10635-1000Neostigmine bromide (Prostigmin) 1000mg
RM-N051504-01Neostigmine Bromide Impurity 4
RM-N051514-01Neostigmine Bromide Impurity 14
RM-N051507-01Neostigmine Bromide Impurity 7

Popular Products