Quinolinic acid (Standard)
CAT:
804-HY-100807R-02
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Quinolinic acid (Standard)
- CAS Number: 89-00-9
- UNSPSC Description: Quinolinic acid (Standard) is the analytical standard of Quinolinic acid. This product is intended for research and analytical applications. Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction[1][2].
- Target Antigen: Endogenous Metabolite; iGluR
- Type: Reference Standards
- Related Pathways: Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
- Field of Research: Inflammation/Immunology; Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/quinolinic-acid-standard.html
- Purity: 99.96
- Smiles: O=C(C1=NC=CC=C1C(O)=O)O
- Molecular Weight: 167.12
- References & Citations: [1]Heyes MP, et al. Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease. Brain. 1992 Oct;115 ( Pt 5):1249-73.|[2]Jang S, et al. Neuroprotective effects of (-)-epigallocatechin-3-gallate against quinolinic acid-induced excitotoxicity via PI3K pathway and NO inhibition. Brain Res. 2010 Feb 8;1313:25-33.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
- Clinical Information: No Development Reported