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Integrin beta 1 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18335759-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18335759-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival. The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities��
Product Name Alternative
Integrin β1; CD29; FNRB; Fibronectin receptor beta subunit; ITB1; Integrin VLA-4 beta subunit
UniProt
P05556
Reactivity
Human
Immunogen
A synthesized peptide derived from human Integrin beta 1
Clonality
Monoclonal
Conjugation
Unconjugated
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000 IHC 1:50~1:200
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IHC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · P05556

Integrin beta-1

ITB1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P05556
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ITGB1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A8K6N2, D3DRX9, D3DRY3, D3DRY4, D3DRY5, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647, Q29RW2, Q7Z3V1, Q8WUM6
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bondGlycoproteinIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Ligand

CalciumMagnesiumMetal-binding

Biological process

Cell adhesionHost-virus interactionMyogenesis

Cellular component

Cell junctionCell membraneCell projectionEndosomeMembrane

Domain

EGF-like domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

Host cell receptor for virus entryIntegrinReceptor

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