c-Jun (Phospho Ser249) rabbit pAb
CAT:
855-ES20155-02
Size:
100 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
c-Jun (Phospho Ser249) rabbit pAb
- Description: Function: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. PTM: Phosphorylation enhances the transcriptional activity. Phosphorylated by PRKDC. similarity: Belongs to the bZIP family. similarity: Belongs to the bZIP family. Jun subfamily. similarity: Contains 1 bZIP domain. subunit: Heterodimer with either FOS or BATF3. Interacts with HIVEP3 (By similarity). Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA.
- Synonyms: Transcription factor AP-1 (Activator protein 1;AP1;Proto-oncogene c-Jun;V-jun avian sarcoma virus 17 oncogene homolog;p39)
- Gene ID: 3725
- UniProt: P05412
- Cellular Locus: Nucleus.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Synthesized peptide derived from human c-Jun (Phospho Ser249)
- Clonality: Polyclonal
- Validated Applications: WB, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:1000-2000 ELISA 1:5000-20000
- Molecular Weight: 39-42kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.