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SHP2 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18335395-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18335395-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily. It participates in signaling events downstream of receptors for growth factors, cytokines, hormones, antigens, and extracellular matrices in the control of cell growth, differentiation, migration, and death.
Product Name Alternative
Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; SH-PTP2; PTP2C; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SHP-2; Shp2; SH-PTP3; PTPN11; SHPTP2
UniProt
Q06124
Reactivity
Human
Immunogen
A synthesized peptide derived from human SHP2
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
Affinity-chromatography
Dilution
WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IHC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q06124

Tyrosine-protein phosphatase non-receptor type 11

PTN11_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q06124
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PTPN11
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.1.3.48
Processing
—
Secondary accessions
A8K1D9, Q96HD7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Disease

DeafnessDisease variant

Molecular function

HydrolaseProtein phosphatase

Domain

RepeatSH2 domain

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