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Rad50 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18334866-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18334866-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A.
Product Name Alternative
HRAD50; Mrell; NBSLD; Rad 50; RAD50 2; rad50; RAD50 homolog (S cerevisiae) ; RAD50 PEN; RAD502; Rad50l
UniProt
Q92878
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Rad50
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000 ICC/IF 1:50~1:200
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q92878

DNA repair protein RAD50

RAD50_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q92878
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RAD50
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
hRAD50
EC number
3.6.-.-
Processing
—
Secondary accessions
B9EGF5, O43254, Q6GMT7, Q6P5X3, Q9UP86
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-bindingZinc

Biological process

Cell cycleDNA damageDNA repairHost-virus interactionMeiosis

Cellular component

ChromosomeNucleusTelomere

Domain

Coiled coil

Molecular function

Hydrolase

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