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EHMT2 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18301659-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18301659-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones.
Product Name Alternative
Bat8; Ehmt2; Euchromatic histone lysine methyltransferase 2; G9a protein; GAT8; Histone H3 K9 methyltransferase 3; NG36
UniProt
Q96KQ7
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from EHMT2
Clonality
Monoclonal
Conjugation
Unconjugated
Source
Recombinant Rabbit
Field of Research
Epigenetics & Chromatin
Purification
Affinity-chromatography
Dilution
WB:1:500~1:2000IHC:1:50~1:200ICC/IF:1:50~1:200IP:1:50FC:1:50
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Molecular Weight
160,170kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, IHC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q96KQ7

Histone-lysine N-methyltransferase EHMT2

EHMT2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96KQ7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EHMT2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.1.1.-, 2.1.1.367
Processing
—
Secondary accessions
B0UZY2, Q14349, Q5JP83, Q5JQ92, Q5JQA1, Q5JQG3, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Domain

ANK repeatRepeat

Molecular function

Chromatin regulatorMethyltransferaseTransferase

Cellular component

ChromosomeNucleus

Ligand

Metal-bindingS-adenosyl-L-methionineZinc

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