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TRIM24 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18334249-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18334249-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac) .
Product Name Alternative
HTIF1; PTC6; RNF82; TF1A; TIF1; TIF1A; TIF1ALPHA; Trim24
UniProt
O15164
Reactivity
Human
Immunogen
A synthesized peptide derived from human TRIM24
Clonality
Monoclonal
Conjugation
Unconjugated
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IHC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · O15164

Transcription intermediary factor 1-alpha

TIF1A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O15164
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TRIM24
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
TIF1-alpha
EC number
2.3.2.27
Processing
—
Secondary accessions
A4D1R7, A4D1R8, O95854
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Domain

BromodomainCoiled coilRepeatZinc-finger

Cellular component

CytoplasmMitochondrionNucleus

Molecular function

DNA-bindingRepressorTransferase

PTM

Isopeptide bondMethylationPhosphoproteinUbl conjugation

Ligand

Metal-bindingZinc

Biological process

TranscriptionTranscription regulationUbl conjugation pathway

Disease

Tumor suppressor

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