Nω-Propyl-L-arginine (hydrochloride)
CAT:
804-HY-102062A-02
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Nω-Propyl-L-arginine (hydrochloride)
- CAS Number: 2321366-46-3
- UNSPSC Description: Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) hydrochloride is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine hydrochloride displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS)[1][2].
- Target Antigen: NO Synthase
- Type: Reference compound
- Related Pathways: Immunology/Inflammation
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/nω-propyl-l-arginine-hydrochloride.html
- Purity: 98.28
- Solubility: DMSO : 25 mg/mL (ultrasonic;warming)
- Smiles: N[C@@H](CCCNC(NCCC)=N)C(O)=O.[H]Cl
- Molecular Weight: 252.74
- References & Citations: [1]Zhang HQ, et al. Potent and selective inhibition of neuronal nitric oxide synthase by N omega-propyl-L-arginine. J Med Chem. 1997 Nov 21;40(24):3869-70.|[2]Klamer D, et al. The neuronal selective nitric oxide synthase inhibitor, Nomega-propyl-L-arginine, blocks the effects of phencyclidine on prepulse inhibition and locomotor activity in mice. Eur J Pharmacol. 2004 Oct 25;503(1-3):103-7.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported