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ACV Tripeptide (TFA)

CAT: 0804-HY-P3519A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P3519A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ACV Tripeptide TFA, a tripeptide, is the first dedicated intermediate in the biosynthetic pathway leading to the penicillin and cephalosporin classes of β-lactam natural products in bacteria and fungi. ACV Tripeptide TFA is is synthesized nonribosomally by the ACV synthetase (ACVS) enzyme, which is encoded by the 11 kb The pchAB gene encodes this enzyme. ACV Tripeptide TFA can be used for the biosynthesis of β-lactam antibiotics[1][2].
UNSPSC
12352209
Target
Drug Intermediate
Type
Peptides
Related Pathways
Others
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/acv-tripeptide-tfa.html
Purity
98.62
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CC(C)[C@H](C(O)=O)NC([C@H](CS)NC(CCC[C@H](N)C(O)=O)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C16H26F3N3O8S
Molecular Weight
477.45
References & Citations
[1]Martin JF, et al. Alpha-aminoadipyl-cysteinyl-valine synthetases in beta-lactam producing organisms. From Abraham's discoveries to novel concepts of non-ribosomal peptide synthesis. J Antibiot (Tokyo) . 2000 Oct;53 (10) :1008-21. |[2]Tahlan K, et al. δ- (l-α-Aminoadipyl) -l-cysteinyl-d-valine synthetase (ACVS) : Discovery and perspectives[J]. Journal of Industrial Microbiology and Biotechnology, 2017, 44 (4-5) : 517-524.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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