ACV Tripeptide

• Description:

  ACV Tripeptide, a tripeptide, is the first dedicated intermediate in the biosynthetic pathway leading to the penicillin and cephalosporin classes of β-lactam natural products in bacteria and fungi. ACV Tripeptide is is synthesized nonribosomally by the ACV synthetase (ACVS) enzyme, which is encoded by the 11 kb The pchAB gene encodes this enzyme. ACV Tripeptide can be used for the biosynthesis of β-lactam antibiotics[1][2].

• UNSPSC:

  12352209

• Target:

  Drug Intermediate

• Type:

  Peptides

• Related Pathways:

  Others

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/acv-tripeptide.html

• Purity:

  98.74

• Solubility:

  H2O : 12.5 mg/mL (ultrasonic)

• Smiles:

  CC (C) [C@H] (C (O) =O) NC ([C@H] (CS) NC (CCC[C@H] (N) C (O) =O) =O) =O

• Molecular Formula:

  C14H25N3O6S

• Molecular Weight:

  363.43

• References & Citations:

  [1]Martin JF, et al. Alpha-aminoadipyl-cysteinyl-valine synthetases in beta-lactam producing organisms. From Abraham's discoveries to novel concepts of non-ribosomal peptide synthesis. J Antibiot (Tokyo) . 2000 Oct;53 (10) :1008-21. |[2]Tahlan K, et al. δ- (l-α-Aminoadipyl) -l-cysteinyl-d-valine synthetase (ACVS) : Discovery and perspectives[J]. Journal of Industrial Microbiology and Biotechnology, 2017, 44 (4-5) : 517-524.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  32467-88-2