HCV-IN-45

• UNSPSC Description:

  HCV-IN-45 (Compound EI-1) is an inhibitor for hepatitis C virus (HCV), that inhibits 1a and 1b HCV pseudoparticles with EC50 of 0.134 and 0.027 μM. HCV-IN-45 inhibits 1a/2a and 1b/2a cell culture-adapted HCV (HCVcc), with EC50 of 0.024 and 0.012μM. HCV-IN-45 inhibits the entry of the virus into hepatocyte, and blocks the cell-cell spread[1].

• Target Antigen:

  HCV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/hcv-in-45.html

• Smiles:

  FC(F)(COC1=NC(NC2=CC=C(C=C2)[N+]([O-])=O)=NC(NCCCCC)=N1)F

• Molecular Weight:

  400.36

• References & Citations:

  [1]Baldick CJ, et al., A novel small molecule inhibitor of hepatitis C virus entry. PLoS Pathog. 2010 Sep 2;6(9):e1001086.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  301211-35-8