HCV-IN-4

• UNSPSC Description:

  HCV-IN-4 is a potent and orally active HCV NS5A inhibitor, shows great potency against GT1a, GT2b, GT3a, GT1a Y93H and GT1a L31V, with EC90s of 3 pM, 0.3 nM, 0.01 nM, 0.5 nM and 0.02 nM, respectively[1].

• Target Antigen:

  HCV

• Type:

  Peptides

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/hcv-in-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  FC1=CC(C2=CN=C([C@@H]3CCCN3C([C@H](C(C)C)NC(OC)=O)=O)N2)=CC4=C1C5=CC6=CC(C7=CN=C([C@H]8N(C([C@H](C(C)C)NC(OC)=O)=O)CCC8)N7)=CC=C6N5[C@H](C9=CC=C(CCCO%10)C%10=C9)O4

• Molecular Weight:

  956.07

• References & Citations:

  [1]Yu W, et al. Discovery of Chromane Containing Hepatitis C Virus (HCV) NS5A Inhibitors with Improved Potency against Resistance-Associated Variants. J Med Chem. 2016 Nov 23;59(22):10228-10243. Epub 2016 Nov 9.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2058080-25-2