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(+) -Menthol

CAT: 0804-HY-W017277-03Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W017277-03Size:500 mg
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Description
(+) -Menthol (D-Menthol) is one of the optical isomers of Menthol. (+) -Menthol can reduce the electrically evoked contractions of rat phrenic hemidiaphragm in vitro. Local anaesthetic activity. (+) -Menthol inhibits fungal growth and sporulation. (+) -Menthol can also inhibit the growth of Microcystis aeruginosa cells[1][2][3][4].
CAS Number
15356-60-2
Product Name Alternative
D-Menthol
UNSPSC
12352211
Hazard Statement
H315, H318, H335
Target
Fungal
Type
Natural Products
Related Pathways
Anti-infection
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/plus-menthol.html
Concentration
10mM
Purity
99.95
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC([C@@H]1[C@H](C[C@H](CC1)C)O)C
Molecular Formula
C10H20O
Molecular Weight
156.27
Precautions
H315, H318, H335
References & Citations
[1]Galeotti N, et al. Local anaesthetic activity of (+) - and (-) -menthol. Planta Med. 2001 Mar;67 (2) :174-6.|[2]Galeotti N, et al. Menthol: a natural analgesic compound. Neurosci Lett. 2002 Apr 12;322 (3) :145-8.|[3]Hu X, et al. Effects of d-menthol stress on the growth of and microcystin release by the freshwater cyanobacterium Microcystis aeruginosa FACHB-905. Chemosphere. 2014 Oct;113:30-5.|[4]José S. Dambolena, et al. Effects of menthol stereoisomers on the growth, sporulation and fumonisin B1 production of Fusarium verticillioides. Food Chemistry. Volume 123, Issue 1, 1 November 2010, Pages 165-170.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Chemical Information

(+)-Menthol

(+)-menthol is a p-menthan-3-ol which has (1S,2R,5S)-stereochemistry. In contrast to ()-menthol, the (+)-enantiomer occurs only rarely in nature. It is an enantiomer of a (-)-menthol.

CAS Number15356-60-2
PubChem CID165675
IUPAC Name(1S,2R,5S)-5-methyl-2-propan-2-ylcyclohexan-1-ol
Molecular FormulaC10H20O
Molecular Weight156.26
XLogP3
Topological Polar Surface Area20.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count1
Heavy Atom Count11
Formal Charge0
Complexity120
SMILES
C[C@H]1CC[C@@H]([C@H](C1)O)C(C)C
InChI
InChI=1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10-/m0/s1
InChIKey
NOOLISFMXDJSKH-AEJSXWLSSA-N
Chemical Structure
2D Structure
2D structure of (+)-Menthol
CAS: 15356-60-2
CID: 165675
Formula: C10H20O
MW: 156.26
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight156.26
XLogP33
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count1
Exact Mass156.151415257
Monoisotopic Mass156.151415257
Topological Polar Surface Area20.2 Ų
Heavy Atom Count11
Formal Charge0
Complexity120
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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