Products for Research Use Only

GCLC Antibody (Center)

CAT: 0013-GTR18329742-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18329742-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Product Name Alternative
Glutamate--cysteine ligase catalytic subunit, GCS heavy chain, Gamma-ECS, Gamma-glutamylcysteine synthetase, GCLC, GLCL, GLCLC
UniProt
P48506
Reactivity
Human, Mouse
Immunogen
This GCLC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-315 amino acids from the Central region of human GCLC. Antigen Region: 286-315 aa.
Target
GCLC (HGNC:4311)
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology, Metabolism Research, Signal Transduction
Dilution
WB - 1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Molecular Weight
72766 Da
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Prediction Reactivity
Rat
Tested Applications
WB
NCBI Accession Number
NP_001489.1, NP_001184044.1
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · P48506

Glutamate--cysteine ligase catalytic subunit

GSH1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P48506
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GCLC
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
6.3.2.2
Processing
—
Secondary accessions
Q14399
Protein keywords

PTM

AcetylationPhosphoprotein

Ligand

ATP-bindingNucleotide-binding

Disease

Disease variantHereditary hemolytic anemia

Biological process

Glutathione biosynthesis

Molecular function

Ligase

Technical term

Proteomics identificationReference proteome