Anti-FABP5 (Marker of Metastatic Potential in Colorectal Cancer)(FABP5/3750)
CAT:
37-BNUM3750-50
Size:
50 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-FABP5 (Marker of Metastatic Potential in Colorectal Cancer)(FABP5/3750)
- Description: This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: FABP5; E-FABP; EFABP; PA-FABP; PAFABP
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: FABP5
- Gene ID: 2171
- NCBI Gene ID: 408061
- UniProt: Q01469
- Cellular Locus: Nucleus & cytoplasm
- Host: Mouse
- Species Reactivity: Human
- Immunogen: Recombinant full-length human FABP5 protein
- Target Antigen: FABP5
- Clonality: Monoclonal
- Isotype: IgG2a κ
- Clone: FABP5/3750
- Conjugation: Purified, BSA-free
- Source: Animal
- Applications: IHC, FFPE (verified) | WB (verified)
- Validated Applications: IHC, FFPE, WB
- Positive Control: MOLT-4 and HEK-293 cell lines. Esophagus, Skin. Keratinocytes; highly expressed in psoriatic skin. Colon.
- Concentration: 1 mg/mL
- Buffer: PBS, no BSA, no azide
- Molecular Weight: 15.4 kDa
- Shipping Conditions: Room temperature
- Storage Conditions: -35°C to -5°C ; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years