Anti-LMO2 (B-Cell Marker)(LMO2/3147R), Biotin conjugate

Anti-LMO2 (B-Cell Marker)(LMO2/3147R), Biotin conjugate

• Description: The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma. The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin. LMO2 is useful in differentiating follicular lymphoma (LMO2 ) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin's and Burkitt's lymphomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
• Synonyms: Cysteine-rich protein TTG-2; LIM domain only protein 2; LMO-2; RBTN L1; RBTN2; Rhombotin like 1; Rhombotin-2 (RHOM2); T-cell translocation protein 2; TTG2
• CAS Number: 9007-83-4
• UNSPSC: 41116161
• UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
• Gene Name: LMO2
• Gene ID: 4005
• NCBI Gene ID: 34560
• UniProt: P25791
• Cellular Locus: Nucleus
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Recombinant fragment (around aa 23-140) human LMO2 protein (exact sequence is proprietary)
• Target Antigen: LMO2
• Clonality: Recombinant Monoclonal
• Isotype: IgG
• Clone: LMO2/3147R
• Conjugation: Biotin
• Disease: Tumor
• Source: Animal
• Applications: Flow, intracellular (verified) | IF (verified)
• Validated Applications: FC, IF
• Positive Control: K562, Ramos or Raji cells. Placenta, pancreas or Hodgkin s lymphoma.
• Concentration: 0.1 mg/mL
• Buffer: PBS, 0.1% BSA, 0.05% azide
• Molecular Weight: 24 kDa
• Additionnal Information: Flow cytometry: 1-2 ug/million cells; Immunofluorescence: 1-2 ug/mL; Optimal dilution for a specific application should be determined.|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
• Shipping Conditions: Room temperature
• Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
• Shelf Life: 2 years