Anti-LMO2 (B-Cell Marker)(LMO2/3147R)
CAT:
37-BNUB3147-100
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-LMO2 (B-Cell Marker)(LMO2/3147R)
- Description: The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma. The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin. LMO2 is useful in differentiating follicular lymphoma (LMO2 ) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin's and Burkitt's lymphomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: Cysteine-rich protein TTG-2; LIM domain only protein 2; LMO-2; RBTN L1; RBTN2; Rhombotin like 1; Rhombotin-2 (RHOM2); T-cell translocation protein 2; TTG2
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: LMO2
- Gene ID: 4005
- NCBI Gene ID: 34560
- UniProt: P25791
- Cellular Locus: Nucleus
- Host: Rabbit
- Species Reactivity: Human
- Immunogen: Recombinant fragment (around aa 23-140) human LMO2 protein (exact sequence is proprietary)
- Target Antigen: LMO2
- Clonality: Recombinant Monoclonal
- Isotype: IgG
- Clone: LMO2/3147R
- Conjugation: Purified, with BSA
- Disease: Tumor
- Source: Animal
- Applications: Flow, intracellular (verified) | IF (verified)
- Validated Applications: FC, IF
- Positive Control: K562, Ramos or Raji cells. Placenta, pancreas or Hodgkin s lymphoma.
- Concentration: 0.2 mg/mL
- Buffer: PBS, 0.05% BSA, 0.05% azide
- Molecular Weight: 24 kDa
- Additionnal Information: Flow cytometry: 1-2 ug/million cells; Immunofluorescence: 1-2 ug/mL; Optimal dilution for a specific application should be determined.|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years