Anti-c-Myc Oncoprotein(MYC2895R), CF594 conjugate
CAT:
37-BNC942895-500
Size:
500 µL
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-c-Myc Oncoprotein(MYC2895R), CF594 conjugate
- Description: The epitope of this antibody spans the Myc tag epitope, aa 410-419 (EQKLISEEDL), which is a specific portion of an alpha helical region of human c-myc protein. Because the epitope is located at the dimerization site of the protein, the antibody is not sensitive for detecting endogenous c-myc, making it suitable for detecting Myc tagged proteins or myc overexpression. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease._x000D_ _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_
- Synonyms: Class E basic helix-loop-helix protein 39 (bHLHe39); MRTL; Myc2; Niard; Nird; Proto-oncogene c-Myc; RNCMYC; Transcription factor p64; Transcriptional regulator Myc-A; V-Myc avian myelocytomatosis viral oncogene homolog
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: MYC
- Gene ID: 4609
- NCBI Gene ID: 202453
- UniProt: P01106
- Cellular Locus: Nucleus
- Host: Rabbit
- Species Reactivity: Human
- Immunogen: A synthetic peptide, corresponding to aa 408-439 (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) from C-terminus of human c-myc, coupled to KLH.
- Target Antigen: c-Myc Oncoprotein
- Clonality: Recombinant Monoclonal
- Isotype: IgG
- Clone: MYC2895R
- Conjugation: CF594
- Source: Animal
- Applications: Flow, intracellular (verified)
- Validated Applications: FC,
- Field of Research: Cancer, Cell cycle, Transcription factors
- Positive Control: K562, HL-60 cells. Cervical Carcinoma.
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: 62-64 kDa
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years