Login

Anti-c-Myc Oncoprotein(MYC2895R), CF594 conjugate

CAT:
37-BNC942895-100
Size:
100 µL
Price:
Ask
For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Anti-c-Myc Oncoprotein(MYC2895R), CF594 conjugate - image 1
Anti-c-Myc Oncoprotein(MYC2895R), CF594 conjugate - image 2
Thumbnail 1
Thumbnail 2

Anti-c-Myc Oncoprotein(MYC2895R), CF594 conjugate

  • Description: The epitope of this antibody spans the Myc tag epitope, aa 410-419 (EQKLISEEDL), which is a specific portion of an alpha helical region of human c-myc protein. Because the epitope is located at the dimerization site of the protein, the antibody is not sensitive for detecting endogenous c-myc, making it suitable for detecting Myc tagged proteins or myc overexpression. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease._x000D_ _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_
  • Synonyms: Class E basic helix-loop-helix protein 39 (bHLHe39); MRTL; Myc2; Niard; Nird; Proto-oncogene c-Myc; RNCMYC; Transcription factor p64; Transcriptional regulator Myc-A; V-Myc avian myelocytomatosis viral oncogene homolog
  • CAS Number: 9007-83-4
  • UNSPSC: 41116161
  • UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
  • Gene Name: MYC
  • Gene ID: 4609
  • NCBI Gene ID: 202453
  • UniProt: P01106
  • Cellular Locus: Nucleus
  • Host: Rabbit
  • Species Reactivity: Human
  • Immunogen: A synthetic peptide, corresponding to aa 408-439 (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) from C-terminus of human c-myc, coupled to KLH.
  • Target Antigen: c-Myc Oncoprotein
  • Clonality: Recombinant Monoclonal
  • Isotype: IgG
  • Clone: MYC2895R
  • Conjugation: CF594
  • Source: Animal
  • Applications: Flow, intracellular (verified)
  • Validated Applications: FC,
  • Field of Research: Cancer, Cell cycle, Transcription factors
  • Positive Control: K562, HL-60 cells. Cervical Carcinoma.
  • Concentration: 0.1 mg/mL
  • Buffer: PBS, 0.1% BSA, 0.05% azide
  • Molecular Weight: 62-64 kDa
  • Shipping Conditions: Room temperature
  • Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
  • Shelf Life: 2 years

Datasheet

MSDS