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Toltrazuril sulfoxide

CAT: 0804-HY-136438-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-136438-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Toltrazuril sulfoxide is a short-lived intermediary metabolite of Toltrazuril , and then can be metabolized to the reactive toltrazuril sulfone (TZR-SO2) in vivo. Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites[1].
CAS Number
69004-15-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/toltrazuril-sulfoxide.html
Purity
99.55
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(N(C1=CC=C(OC2=CC=C(S(C(F)(F)F)=O)C=C2)C(C)=C1)C(N3)=O)N(C)C3=O
Molecular Formula
C18H14F3N3O5S
Molecular Weight
441.38
Precautions
H302, H315, H319, H335
References & Citations
[1]Jong-Hwan Lim, et al. Pharmacokinetics of toltrazuril and its metabolites, toltrazuril sulfoxide and toltrazuril sulfone, after a single oral administration to pigs. J Vet Med Sci. 2010 Aug;72 (8) :1085-7.|[2]H Mehlhorn, et al. Toltrazuril effective against a broad spectrum of protozoan parasites. Parasitol Res. 1988;75 (1) :64-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Coccidia

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